To uncover the general market conditions and tendencies, Neglected Tropical Diseases Treatment market research report acts as a perfect source. This report puts light on many aspects related to industry and market. Market definition, market segmentation, competitive analysis and research methodology are the major topics covered in this report. Data collection modules with large sample sizes are used to collect data and perform base year analysis. This market report gives information about company profile, product specifications, capacity, production value, and market shares for each company under the competitive analysis study.Market Analysis: Global Neglected Tropical Diseases Treatment Market
December 1, 2019Opinion Consider personal side of data collection II
Washington D.C. USA , Nov 30 (ANI): In what could be a piece of great news for men with advanced prostate cancer, a new study has claimed that they can live two more years or even more on immunotherapy.Yes, the study published in the Journal of Clinical Oncology has found that those with advanced prostate cancer who have exhausted all other treatment options could benefit from immunotherapy.Researchers also found that a small proportion of men were ''super responders' and were alive and well even after the trial had ended despite having had a very poor prognosis before treatment.They found that one in 20 men with end stage prostate cancer responded to the immunotherapy pembrolizumab but although the number who benefited was small, these patients sometimes gained years of extra life.The most dramatic responses came in patients whose tumours had mutations in genes involved in repairing DNA, and the researchers are investigating whether this group might especially benefit from immunotherapy.The phase II clinical trial was led globally by a team at The Institute of Cancer Research, London, and The Royal Marsden Foundation Trust, and involved 258 men with advanced prostate cancer who had previously been treated and become resistant to androgen deprivation therapy and docetaxel chemotherapy.Overall, 5 per cent of men treated with pembrolizumab saw their tumours actually shrink or disappear, while a larger group of 19 per cent had some evidence of tumour response with a decrease in prostate specific antigen (PSA) level.Among a group of 166 patients with particularly advanced disease and high levels of PSA, the average length of survival was 8.1 months with pembrolizumab.Nine of these patients saw their disease disappear or partly disappear on scans. And of these, four were super responders who remained on treatment at the end of study follow up, with responses lasting for at least 22 months.Meanwhile, a second group of patients whose PSA levels were lower but whose disease had spread to the bone lived for an average of 14.1 months on pembrolizumab.The study also compared the effectiveness of pembrolizumab in men whose tumours had a protein called PD L1 on the surface of their cancer cells and those whose tumours did not.Targeting PD L1 activity with pembrolizumab takes the 'brakes' off the immune system, setting it free to attack cancer cells.Commenting on the findings, Professor Johann de Bono, Regius Professor of Cancer Research at The Institute of Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said: "Our study has shown that a small proportion of men with very advanced prostate cancer are super responders to immunotherapy and could live for at least two years and possibly considerably longer."Adding to it, Professor Paul Workman, Chief Executive of The Institute of Cancer Research, London, said: "Immunotherapy has had tremendous benefits for some cancer patients and it''s fantastic news that even in prostate cancer, where we don''t see much immune activity, a proportion of men are responding well to treatment." (ANI)
ANANTAPUR: Two children in Class III and Class V were treated in an inhumane manner as their hands and feet were bound with a rope to a bench for their lsquo;mischievous ' behaviour. The incident took place at the Masanampet Upper Primary School in Kadiri mandal of Anantapur district. The headmistress, who is now under inquiry for corporal punishment, has shifted blame on the children ''s parents. Speaking to the media, Sridevi said that the mother of one of the children had come to school, complaining that the boy had not been attending classes regularly. ”His mother beat him up badly, tied him there and left, ” Sridevi said. She added that it was the parents who tied the children ''s hands and feet.
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WhatsApp on Monday announced an investment of $250,000 in the Indian startup ecosystem to help the Indian entrepreneurial community connect with their customers and grow their businesses.Through a partnership with Startup India, a flagship initiative of the Indian government, WhatsApp will give 500 startups, approved by the Department for Promotion of Industry and Internal Trade (DPIIT), $500 each of Facebook ad credits. With the ad credits, the startups can create ads that invite customers to click to open a chat on WhatsApp so they can increase sales.
The world knows late Field Marshal Sam Manekshaw as the man who, as the chief of the Indian army in the 1971 Indo Pakistan War following the Bangladesh Liberation War, made great contributions to the creation of Bangladesh. Sam also fought on the Burma front as a Captain of the 12th Frontier Force and was seriously wounded fighting the Imperial Japanese Army during World War II. But the world is unaware that another Manekshaw Lt Jamshed Manekshaw (Jimmy) was also defending the Indian territory against the Japanese invasion in the Dohazari region of the Chittagong front during World War II. While Sam survived the bullet wounds, Jamshed died in action in Dohazari and he became an unsung martyr. Lt Jamshed Manekshaw died on May 14, 1944.Lt Jamshed belonged to Bulsar in Gujarat state of undivided India and he worked in Kabul in Afghanistan before he joined the Indian army as a commissioned officer. He was sent to fight against the Japanese Imperial forces in the northeast part of India and in the Chittagong s areas. These areas which were then part of the erstwhile East Bengal are now part of Bangladesh. A large number of Indians, British, Australian and Africans died in action fighting here. Based on their religion the last rites of these brave soldiers were performed in the various war cemeteries built by the British army in the region. They were designated military cemeteries where the martyrs were laid to rest with full military honours. Lt Jamshed Manekshaw belonged to the Parsi community in India; the Parsis are Zoroastrians who fled from Iran to settle down in India. The Parsis who settled down in Gujarat after escaping from Iran facing persecution later spread to various parts of India and excelled in business. They contributed to the economy of undivided India and a few families had businesses in Dhaka and Chittagong too. There was one businessman, Mr Merdhora, who lived in Chittagong then and the British took his help in performing the last rites of Lt Jamshed.
The group wants to honor veterans with a memorial and is asking family members to provide them with the names of Kilkenny men and women who served in the war.So far, the committee has received 58 names of those who died in the war and 127 survivors.
Key point: Thanks to the introduction of better fighters and the use of aggressive, realistic offensive fighter doctrines, American airmen attained not the air superiority they sought, but total air supremacy over the whole of western Europe. The popular conception of the struggle in the air over northern Europe during World War II is of squadrons of sleek fighters racing over the German heartland to protect contrailed streams of lumbering bombers stretching beyond sight. This is as it was during the second half of America s air war against Germany, but it was as far from the truth as it is possible to get at the start of that great aerial crusade. It took until late 1943 nearly two years after the United States entered World War II before the United Kingdom based Eighth Air Force mounted strategically significant bombing missions against targets in occupied northern Europe. The fault for this lay partly in the availability and slow development of the equipment, but it is also a fact that the two men at the top of the Eighth Air Force command structure stubbornly clung to old and discredited theories that stunted the effectiveness of the strategic bombing effort and cost thousands of their countrymen their freedom or their lives. In the beginning, the fighter was a short legged creature whose role of protecting the bombers was eclipsed by its role of guarding friendly territory and installations. The difference, which is crucial, was the product of technology range and the power of aircraft engines and intellect. Until late 1943, surprisingly late in the war, the use of the fighter as an offensive weapon was stunted by the defensive mind set of the pursuit acolytes of the interwar decades. The pursuit airplane had evolved over the fixed battlefields of Western Europe during World War I. Pursuit aircraft had been developed to prevent enemy reconnaissance airplanes from overflying friendly lines and to protect friendly observation airplanes from enemy pursuits while the observers overflew enemy lines. The pursuit was conceived as a tactical and a defensive weapon, and it was limited to these roles both by conception and by the technologies of the day. The Army Air Corps Between the world wars, the development of American pursuit aircraft was hobbled by budgetary restrictions that for many years slowed or obviated altogether the creation of new technologies or even methodical experimentation with new tactics. The U.S. Marine Corps did advance the use of the single engine pursuit as a nascent close support weapon to bolster the infantry, but the interests of various intra Army constituencies prevented similar advances in what had come to be called the Army Air Corps. To the degree that it developed at all, the Air Corps saw increasingly heavy and longer ranged bombers in its future. And, as the limited available research and development dollars were expended on speedier bombers, the pursuits of the day were increasingly outranged and outrun. Inevitably, American bombers of the late 1930s were designed to be self defending because they could fly much farther and at least somewhat faster than could the pursuits of the day. The pursuits, which were being developed at a much slower pace, were relegated to a point defense role guarding cities, industrial targets, and air bases. When World War II began, the Air Corps shortly to be renamed the Army Air Forces was divided into two distinct combat arms, fighters and bombers. And, by virtue of the fighter s stunted development, there appeared little chance that the two would spend much time working together. As soon as the Army Air Corps was pulled into World War II it became focused on the defense of American coastal cities, several Caribbean islands, bases in Greenland and Iceland, and on the strategically indispensable Panama Canal. There were few airplanes of any type to devote to these defensive missions, and those that were deployed defensively also had to serve as on the job trainers for hundreds of the raw young pilots emerging from the Air Forces burgeoning flight schools. Through the first half of 1942, all of the very few pilots and airplanes that could be spared from the defense of the U.S. coasts and sea lanes were rushed to defend Australia and the South Pacific. Dozens of precious airplanes and pilots were lost in the pathetic defense of Java, in the Netherlands East Indies, and many more were lost in the early defensive battles around Port Moresby, New Guinea, but Army Air Forces training commands were able to catch up with combat and training losses as well as with the heavy burden imposed by the formation of new fighter, bomber, and other type groups. And better fighters with a higher probability of survival began to reach operational air groups. Committing to American Air Power Fortunately, the United States could afford to be a bit late off the mark in her war against Germany. German efforts in 1940 to bring Great Britain to her knees all had failed miserably and, by the end of 1941, the bulk of Germany s air and land forces were mired in a frightful war of attrition deep inside Russia. The British had the situation in northern Europe reasonably well in hand, though they would have collapsed had not vast infusions of weapons and supplies from the United States sustained them. British forces in Egypt and Libya were teetering on the edge of defeat, but there was little the United States would be able to do for many months to influence the outcome assuming the British held on that long. So, while the Army Air Forces devoted the bulk of its limited expendable resources to defensive measures against Japan, new air groups were created, and new and better combat aircraft began rolling off newly created assembly lines. Finally, in the spring of 1942, it was decided in high Army Air Forces circles to commit American air power to northern Europe. At first, the commitment would be little more than a meager show of force masking an advanced combat training program overseen by the Royal Air Force (RAF). Only later, when training bases and factories in the United States had caught up with the planning, would the U.S. Army Air Forces take on a strategic air campaign against the German industrial heartland. Brigadier General Ira Eaker arrived in England on February 20, 1942 to establish the headquarters of the new VIII Bomber Command. He opened his headquarters at High Wycombe, England on February 23, 1942, but the VIII Bomber Command had no combat airplanes to its name; they would not be available for several months. Rather, it fell to Eaker to argue with his British hosts in favor of an independent role for the forthcoming Army Air Forces in Europe. The RAF and the British government wanted America s commitment to the air war in Europe to be subordinate to or an adjunct of the British Theatre air war. The Americans, however, felt they deserved an independent role, and it was Eaker s job to win the British over to this viewpoint. The American notion was strongly bolstered in argument, at least by the fact that the Army Air Forces had developed over many years a theoretical strategic air doctrine that was quite different from the RAF s experience based strategic doctrine. The Americans favored and had equipped their bomber force to wage a precision daylight bombing campaign against industrial targets hundreds of miles inside enemy territory. The RAF was the only other air force in the world that had developed long range, four engine, heavy bombers, but its doctrine the result of bloody experiences early in the war favored area bombing at night. Doctrinal arguments aside, the British victims of the Nazi Blitz of 1940 1941 were less squeamish than their American Allies about bombing German civilians. Besides, the RAF had few long range heavy bombers to its name, and thus felt it needed to co opt the promised infusion of American heavies. For the time being, Eaker s arguments with the RAF hierarchy were moot. There would be no American air combat units in the United Kingdom for several months, and then there would not be enough of them to make a dent in Hitler s Fortress Europa for many more months. A Symbolic Commitment between Allies The first VIII Bomber Command unit to arrive in England on May 10, 1942 was the 97th Heavy Bombardment Group, which was equipped with Boeing B 17 Flying Fortress four engine heavy bombers. This was a symbolic commitment, for the 97th had been activated in February 1942 and thus had not had time to be adequately trained to fly combat missions over heavily defended European targets. It would be months before the 97th saw any live action. Around the time the 97th Heavy Bombardment Group became the first nominal combat unit to join Eaker s VIII Bomber Command, Brig. Gen. Frank Monk Hunter arrived in England to establish the headquarters of his VIII Fighter Command, also at High Wycombe. Unlike Eaker, Hunter, a rather flamboyant World War I ace, quickly came to terms with British beliefs and aspirations regarding the employment of forthcoming American fighter groups. The RAF had opted for powerful, short range, point defense fighters that could defend friendly air bases and attack nearby enemy air bases, and its doctrine appeared to have proven itself during the Battle of Britain and the Blitz. Hunter, who had spent most of his career arguing the point defense case for the U.S. Army s fighters, was eager to augment the British fighter plan. 1 2 3 4 Next View the discussion thread. copy; Copyright 2019 Center for the National Interest All Rights Reserved
David Bowie, wrapping up European stint of his now iconic Isolar II in 1978, performed a monster a three night residency at London s Earls Court in late June and early July to wide critical acclaim. The song, co written by Bowie and Brian Eno, was famously produced by Tony Visconti in the shadows of the Berlin Wall back in 1977. A year later, while touring the record, the Starman himself used the track as the second song of his momentous performance in London.
A new effort to help the youngest refugees Last Updated Nov 17, 2019 9:07 PM ESTThere are more people living as refugees around the world today than at any time since World War II. And with conflicts dragging on for years, being a refugee now often means not going home for decades. That''s literally a lifetime for millions of young children. The refugee crisis has sparked a partnership between two of this country''s leading non profit institutions: Sesame Workshop, creator of "Sesame Street," and the International Rescue Committee, the IRC, a refugee assistance organization originally founded by Albert Einstein. For 50 years, "Sesame Street" has been teaching young children that one plus one equals two; but by teaming up with the IRC to help the youngest refugees, it''s hoping that one plus one can now add up to far more.
With Frozen II on the horizon, speculation over Elsa;s sexuality is kicking into gear once again with a renewed fervor.Back when the movie first came out and Elsa became a queer icon due to be voiced by Maureen herself, Idina Menzel, and singing "Let It Go, " people have felt like she would be an excellent lesbian princess. After all, Elsa was the rare princess who seemed unconcerned with finding a prince charming. Twitter mobilized, as it does, and generated a #GetElsaAGirlfriend campaign for the sequel to the hit 2013 film.
Les informations retenir : Quelques centaines de manifestants entre 200 et 300 selon nos informations , vacu s de la place d'Italie dans le XIIIe arrondissement de Paris, progressent d sormais en direction des Champs Elys es. Les forces de l'ordre les suivent en queue de cort ge. Pr s du Louvre ont clat des tirs de lacrymog ne. Aux abords de Ch telet, des tensions entre les manifestants et les policiers ont clat en fin d'apr s midi. Les forces de l'ordre ont d cid de fermer le centre commercial des Halles et orientent les personnes qui d filent vers les sorties du m tro.
The top secret reinforced bunker is where Adolf Hitler spent most of his time in the final years of WWII but it was abandoned and partly destroyed in 1945 before Soviet forces could discover it.
16th Nov 2019
An appeal to identify and commemorate Croydon s post World War II fallen heroes has been launched. Those killed in active service up to World War II are commemorated by name in Croydon, but those who died in the years since are not.
"Once I am gone, he will do what I am doing now. Then he will speak my language too," said Mahatma Gandhi in his speech to the AICC on January 25, 1942The background of this speech is the CWC resolution passed in its meeting on 30 December, 1941. The British government had announced India s participation in World War II, without consulting the Indian leaders, and more importantly without committing itself to India s independence after the war. There was widespread resentment and the people were restive with the individual satyagraha . The Bardoli resolution reflected the popular mood and Congress s response to it. The resolution also sought to finetune the doctrinaire insistence on nonviolence both for the Congress party and the future government of India. Nehru was supposed to be main brain behind this resolution and defended it vigorously at the Wardha meeting of AICC in January 1942, sharply attacking its opponents. So sharp was Nehru s attack on absolute reliance on nonviolence even as an instrument of state policy, that it left Rajendra Prasad quite upset as noted by Gandhiji in this speech.