The region has been plagued by narco terrorism. The drug cartels have been very active in the region right from Mexico down to Peru. And this fight against transnational organized crime and drug trafficking has increased the region s requirement for modern protection equipment for their security forces. This makes it a potential market for military stores. Many of the countries and the police military forces of the region are engaged in the modernization of its forces which will give Indian companies the opportunity to exploit that market explained a top diplomat.On the list of systems that are likely to be exported include artillery systems, protected vehicles, electronic warfare, naval combat management system, military communications C4I solutions, small arms, night vision devices, and other related military equipment.In a major policy shift, the government in its first term had notified a new strategy for export of defence products that not only encourages the sale of military equipment to foreign nations.India Chile Defence Cooperation Later this year an Indian Naval Delegation is expected to travel to Chile to attend the EXPONAVAL 2020from December 1 4 at a naval base in that country. An invitation has been extended by the Commander of the Chilean Navy to Indian Navy Chief Admiral Karambir Singh and also for one of the Indian warships to attend an event at Valpariaso during their expo, sources have confirmed to Financial Express Online. Also, an invitation has been extended to M s BrahMos to participate in the event.As per the laws for supply any industrial or defence equipment in Chile, companies all over the world are required to register themselves with the Chilean Armed Forces and the Joint Staff.So far several Indian Companies with the help of the Indian Mission in Santiago have registered themselves with Chilean Armed Forces. Some Indian companies including M s Brahmos; M s Azista Industries;M s Reliance Naval Engineering; M s Goa Shipyard Ltd., are now registered. And registration of some companies including #8212; New Space India Limited; Neo Power; Hindustan Aeronautics Limited; Ordnance Factory Board; and BEML is under process.In March this year, the Chilean Navy has acquired an Anchor Handling Towing Supply and Standby Vessel (AHTSSV) ocean support vessel from Indian shipyard Larsen amp; Toubro Shipbuilding for a value of $ 11.5 million. This unit was part of an order for four supply vessels (PSVs) and two vessels specializing in towing and handling and anchoring of offshore platforms (AHTSSV) made in 2013 by Halul Offshore Services Co. WLL (HOSC) from Qatar to L amp;T Shipbuilding. The delivery of the AHTSSV, with around $ 20 million each, was cancelled by HOSC in 2016 due to the fall in demand for services from the oil industry. The acquisition of the ship, which has been carried out through the Foreign Military Sales (FMS) modality of the United States Department of Defense, will be managed by the Naval Sea Systems Command (Navsea) and the pre delivery work is scheduled to be completed in Chennai, soon, an informed source told Financial Express Online.The Chilean Navy is undergoing modernisation. And India could offer Indian shipyards and industry for major Make in India initiatives. Also, there could be a possibility of co operation in the field of Scorpene Submarines. The Chilean Navy has been operating this class of Submarine since 2005 and has developed considerable operational and maintenance expertise. And from India s point of view, there could be cooperation in training, procedures, documentation, syllabi, maintenance and repair aspects including inventory management without the influence of the OEM, explained a source.What can India do in the region?Delegations from the armed forces can visit these countries. And the Indian government can offer specialized training for officers in Basic and Advanced Mountain Warfare Courses. There could be cross deputation of instructors at respective training establishments. Cross deputation of instructors at respective training establishments; Cross deputation of observers during multinational exercises.The focus markets will be Brazil, Argentina, Chile, Ecuador, Colombia, Bolivia, Mexico, El Salvador, Guatemala, Peru, Honduras and other countries in the region which are looking for body armour, plates, aircraft protection, naval protection, for homeland security bulletproof jackets, helmets, night vision devices, general munitions etc.MSME MKU Company based in the UP Defence Industrial Corridor has been perhaps the only one from India working in the region for a number of years now. And have been regularly supplying body armour for security forces of several of the Latin American countries.Shipbuilding prospects with the South American ShipyardsThree nations in the region have three best shipyards that currently exist in the South American region: COTECMAR Colombia; SIMA Per ; and ASMAR Chile. Though they already have full order books, Indian companies could look at joint ventures in shipbuilding.The attraction for BrahMos MissilesBesides Chile, countries like Brazil too had discussions with the BrahMos officials about the possibility of buying the missiles from India.
In Brazil, President Jair Bolsonaro, 65, announced his illness Tuesday and is using it to publicly extol hydroxychloroquine, the unproven malaria drug that he s been promoting as a treatment for COVID 19 and now takes himself.Bolivian interim President Jeanine A ez, 53, made her own diagnosis public Thursday, throwing her already troubled political prospects into further doubt.
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Kangana, who has been openly speaking about the "emotional lynching " of Sushant Singh Rajput in the film industry wrote, "What about @rajeevmasand? He wrote many blind items on SSR calling him a rapist, skirt chaser, overpaid outsider, drug addict? Just because he writes in English he is celebrated by you all, you can make KRK a punching bag but you don ''t have the courage to call powerful people out "Check out her tweets here.
Shushruta specialised in ophthalmic surgery (extraction of Cataracts). Shushruta was one of the first to study the human anatomy. In the Shusruta Samahita he has described in detail the study of anatomy with the aid of a dead body. Shusruta s forte was rhinoplasty (Plastic surgery) and ophthalmialogy (ejection of cataracts). Shushruta has described surgery under eight heads Chedya (excision), Lekhya (scarification), Vedhya (puncturing), Esya (exploration), Ahrya (extraction), Vsraya (evacuation) and Sivya (Suturing). The practice of surgery has been recorded in India around 800 B.C. This need not come as a surprise because surgery (Shastrakarma) is one of the eight branches of Ayurveda the ancient Indian system of medicine. The Ayurvedic practitioner was called vaidya, meaning a person of profound knowledge, who made use of what is called rational therapy. He examined the individual as a whole and not just his disease, took a careful note of the patient s innate physiology, mental state, and other factors such as age, food habits, and season of occurrence of disease. The vaidya conducted a thorough examination using both direct perception (pratyaksha) and inference (anumana). In addition, oral or written testimony of the personal experience of Ayurvedic experts was also accepted as a diagnostic tool (aptopadesha). The vaidya was also expected to question the patient in great detail (prashna), conduct a thorough physical examination using all his five senses (panchendriya pariksha), and confirm or negate his diagnosis through experimentation (yukti). Laying much emphasis on the vaidya s knowledge of drugs, he was supposed to keep in mind both its therapeutic and adverse effects. The Vaidyas laid equal emphasis on the cure of disease as well as prevention and health promotion. They prescribed a daily and seasonal routine as well as attention to nutrition for maintenance of a balanced state of health.Ayurvedic preceptors conceived the role of a physician as much more than mere treatment of diseases. He was to help an individual reach the ultimate spiritual goal of self emancipation, which would not be possible without a healthy mind and body. He was to educate the people about health and disease, and be able to communicate with the lay public and the scholars alike. This required wisdom and skilled communication. Charaka says this about the goal of the vaidya, Not for self, not for the fulfillment of any earthly desire or gain, but solely for the good of suffering, should you treat your patients and so excel all. Those who sell the treatment of diseases as merchandise gather dust and neglect gold. The ancient texts talk in detail about the doctor patient relationship. A vaidya was expected to be friendly and sympathetic toward his patients so that they do not fear him. Charaka recommends that the vaidya keep his conclusions to himself to avoid potential harm. Ayurvedic texts prohibit physicians from private conversations or indulging in jest with women.
The research focuses on the incurable blood cancer multiple myeloma but could apply to other types of cancers. ”By figuring out how tumor cells evade cancer drugs, we are discovering their vulnerabilities and engineering novels ways to target the cancer, ” said researcher Michaela Reagan, a faculty scientist at the Maine Medical Center Research Institute.
Seeking to facilitate the availability of experimental drugs for severely ill COVID 19 patients, the Union Health Ministry has issued a draft notification for "compassionate use" of any unapproved drug that is in the phase III clinical trial globally.The draft New Drugs and Clinical Trials (Amendment) Rules stipulate the manufacture and import of unapproved drugs based on a prescription by a hospital or medical institution. According to a gazette notification of the draft rules published on June 5, a hospital or medical institution may import the new drug for "compassionate use for the treatment of patients suffering from a life threatening disease or disease causing serious permanent disability or disease requiring therapy for unmet medical need", which has not been permitted in the country, but under Phase III clinical trial (human trial) in the country or abroad, by making an application to the Central Drug Regulator.
Cancer typesCancers in general
Trade boycotts or bans are especially costly when production is organised through global supply chains, as is the case with the pharmaceutical industry. Although India is the third largest producer of finished drugs in the world, it relies significantly on China for supplies of active pharmaceutical ingredients (APIs), the key components in making medicines. An estimated 70 per cent of API requirements of India s pharmaceutical industry are sourced from China. For some drugs, such as paracetamol and ibuprofen, this dependence is almost 100 per cent. This import reliance has been fuelled by environmental controls in India and competition with China, which has higher volumes of production and lower costs. Given this, restricting or banning the import of APIs would cause significant disruption to the Indian pharmaceutical industry which had $40 billion in revenues in 2018 19, according to Pharmexcil.Such a prospect is especially of concern to potential patients. A severe contraction of Indian pharmaceutical production and its almost $20 billion worth of annual exports, would affect access to medicines both in India and globally. The impacts would be especially high in low and middle income countries which have become increasingly dependent on affordable medicines supplied by India. In many African countries, in fact, India supplies almost 50 per cent of the medicines in value terms and even higher percentages in terms of volume.
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Panelists at the conference included Delaware Attorney General Kathleen Jennings, Rep. Nnamdi O. Chukwuocha, D Wilmington North, and Kerri Evelyn Harris, community organizer. Following the death of George Floyd at the hands of a police officer, the panel focused on criminal justice reform, particularly in Sussex County. Jennings noted that there have already been criminal code reforms since 2019. They include a rewrite of the drug code, and expungement of arrest and conviction records. However, she said there is much more that needs to be done.
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15 thousand corona patients reported in just 24 hours
STAFF REPORTERGUWAHATI: What exactly causes liver cancer? Indian scientist Dr Hifzur R Siddique, who hails from Assam, has discovered the protein forming cancerous cells in the human body that cause the growth of tumour in the liver. In the human body, it happens either due to excess alcohol consumption or Hepatitis infection.Dr Siddique who has conducted a research with Prof Keigo Machida of University of Southern California in Los Angeles and other collaborators, told The Sentinel on Saturday that the findings of their research evokes hope for the possible effective treatment of this lethal disease. He added that the research could serve as a potential therapeutic target for the drug design and give a direction to the management strategy for liver cancer.
French pharma company Ipsen has been granted a fast track designation by the US Food and Drug Administration (FDA) for its immunotherapy treatment Onivyde in previously untreated pancreatic cancer. The FDA designation will review the use of Onivyde (liposomal irinotecan) in combination with 5 fluorouracil leucovorin (5 FU LV) and oxaliplatin (OX), also known as Nalirifox, in patients with previously untreated, unresectable, locally advanced and metastatic pancreatic ductal adenocarcinoma (PDAC).
Lurbinectedin will be marketed under the brand name Zepzelca and will be made commercially available in the US in early July by PharmaMar s partner, Jazz Pharmaceuticals. The accelerated approval was based on results from a phase II trial where lurbinectedin shrank the tumors in 35% of patients with relapsed metastatic small cell lung cancer #8212; an aggressive form of lung cancer with a five year survival rate of just 14%.Drugs granted accelerated approval by the FDA typically need phase IV confirmatory trials to confirm the drug s benefits before getting full approval. For reaching the accelerated approval stage with lurbinectedin, Jazz will pay PharmaMar 89M and will hand over an additional 134M when full approval is achieved. PharmaMar could also receive royalties of up to 30% from the drug s sales.
The impact of COVID 19 pandemic has left the world in the biggest shock of this decade. The number of people suffering due to the Coronavirus has been increasing at a rapid pace. Many medical organizations across the globe are working meticulously on developing the vaccine for COVID 19. Furthermore, several organizations are coming together to use their respective specializations and develop a drug that can fight this pandemic. For instance, Vir Biotechnology and National Institute of Health Vaccine Research Centre has formed a partnership to understand the immune responses of various drugs on COVID 19. Government bodies are investing generously in order support the development of drugs; for instance, three Oxford based COVID 19 projects have received an investment of $24.63 billion from the government of UK. Companies are investing hefty amounts in developing various drugs and software that can simplify and help the process of drug discovery; for instance, AlphaFold, an AI system introduced by Google, is helping the organizations in understanding the 3D structure of a protein based on the genetic sequence of the virus The COVID 19 is boosting the global computer aided drug discovery market and expected to upsurge the market growth in the coming years as well. During this unique situation, our analysts are helping our clients in understanding the impact of COVID19 on the Computer aided drug discovery Market by providing them with an in depth analysis. Our report includes:
The global blood cancer drugs market is segmented into blood cancer type, drugs and treatment approaches. On the basis of blood cancer type, the global blood cancer drugs market is segmented into leukemia, lymphoma and myeloma. The lymphoma segment is expected to drive the majority market of blood cancer drugs followed by leukemia. The global market of this segment is primarily driven by the increasing prevalence of lymphoma, and presence of effective treatments in the market. On the basis of drugs, the global blood cancer drugs market is further categorized into Rituaxan Mabthera (Rituximab), Gleevac Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others. This continuous innovation for treating various sub types of blood cancers has led to the development of novel types of treatments. For instance, the combination of Revlimid and Velcade has emerged as the preferential drugs in trials for treating multiple myeloma.