Advances in immunotherapy are improving outcomes for patients with various cancers. In addition, the immunogenicity of breast cancer is leading to increasingly optimistic views on the use of immunotherapy to treat various subtypes of breast cancer, in particular HER2 overexpressing subtype.In this review, researchers from Jordan and the United States describe the immune microenvironment of HER2 positive breast cancer. Current and emerging immunotherapies and their potential in the treatment of breast cancer, including immune checkpoint inhibitors, therapeutic vaccines, and adoptive T cell immunotherapy, are explored.
Dolores Aveiro, a mother of the Juventus star, said she has undergone breast radiotherapy and surgery in Madrid.
To detect breast cancer early, you need to be alert about the changes appearing in your breasts. Watch this video carefully to spot unusual growth in your breasts. Letâ€™s be more aware about breast cancer.
PITTSBURGH (KDKA) About 16,000 pounds of ;fun shapes; chicken nuggets are being recalled.The recall applies to ready to eat 12 ounce packages of PERDUE Fun Shapes Chicken Breast Nuggets.
Researchers at the Fred Hutchinson Cancer Research Center led by Dr. Cyrus Ghajar recently uncovered promising new science in the battle against metastatic breast cancer. Their findings, published today in Nature Cell Biology, show that it s possible to destroy cancer cells that can hide for years in people s bone marrow.Chemotherapy is often effective at destroying fast growing cells, but there s a problem: cancer cells can go dormant and avoid chemotherapy, only to return years later. In patients with the most common form of breast cancer, dormant cells can avoid detection only to wreak havoc again after many years. This process, known as metastasis, is responsible for more than 90 percent of the deaths associated with breast cancer.
Researchers at the University of Basel in Switzerland have found a way to transform breast cancer cells into fat cells by exploiting a pivotal moment in their life cycle. At least, they have in mice. The success of the technique, published in the journal Cancer Cell, hinges on a process called epithelial mesenchymal transition (EMT).
The treatment not only stopped cancer cells from spreading but also transformed them into harmless fat cells.
To achieve this feat, the team exploited a weird pathway that metastasising cancer cells have; their results are just a first step, but it's a truly promising approach.When you cut your finger, or when a foetus grows organs, the epithelium cells begin to look less like themselves, and more 'fluid' changing into a type of stem cell called a mesenchyme and then reforming into whatever cells the body needs.
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Updated: January 10, 2019 12:00 PM EST
The US cancer death rate has steadily dropped since 1991, with a total decline of 27 percent over 25 years, researchers reported yesterday in CA: A Cancer Journal for Clinicians. The deaths from cancer for every 100,000 people dropped from a peak of 215 in 1991 to 156 in 2016. Advances in cancer treatment and detection as well as a decrease in smoking have primarily driven the decrease, according to the authors.Although cancer was still the second leading killer in 2016, the study revealed a decline in deaths from the four major types of cancer: lung, breast, prostate, and colorectal. Lung cancer is the most deadly, but with fewer people smoking, the death rate among men has fallen by almost 50 percent since 1991, reports The Associated Press.
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Scientists at the University of California at Berkeley (USA) have found that children who are exposed to chemicals contained in toothpaste, shampoo and soap, can be prone to premature puberty. This, in turn, contributes to the high risk of mental illness, breast cancer and genital organs, reports the Star.The study involved 388 girls, the health was followed from birth until reaching the age of puberty,Lenta reports.
Reporting their studies in the Journal of Neuroscience, Nicole Gervais, Ph.D., and colleagues say their findings highlight the need both for greater understanding of the mechanisms that underlie how AIs impact on brain function, and also the development of new treatment approaches for breast cancer patients that minimize adverse effects on the brain. Their paper is titled, Adverse effects of aromatase inhibition on the brain and behavior in a non human primate. Estrogens are produced through the conversion of testosterone by the enzyme aromatase, and patients with estrogen receptor dependent breast cancer are commonly treated using adjuvant aromatase inhibitors, such as letrozole, to prevent this conversion. AI therapy is also used for men with prostate or breast cancers. Unfortunately, AI drugs can cause side effects including insomnia, depression, hot flashes, and memory problems that may be severe enough for patients to discontinue treatment, the authors wrote. However, the mechanisms by which AIs give rise to these CNS symptoms remain unclear, they pointed out, as studies in humans often lack proper controls and are hampered by confounding factors such as concurrent chemotherapy radiotherapy treatment, stress, and disease stage. There have also not been any systematic analyses of sex related differences in side effects.
Obesity is emerging to be one of the top health concerns around the world. If the findings of a latest study are to be believed, excess body weight is said to be responsible for 3.9 percent of cancer globally. The study, published in the journal Cancer, spoke about association between obesity and the risk of 13 types of cancers, including postmenopausal breast cancer and liver cancer, and a probable relationship with three other cancers, including prostate cancer. "In particular, not many people are aware of the link of overweight obesity to cancer risk," said Hyuna Sung, a participant researcher of the study.
Sondra Locke has died at the age of 74.The Oscar nominated actress passed away at her Los Angeles home after suffering a cardiac arrest stemming from breast and bone cancer.